Home Amplifiers Fully differential amplifiers
Home
Amplifiers
Fully differential amplifiers

THS4541

ACTIVE

High-Speed Differential I/O Amplifier

Order now
Data sheet

THS4541

ACTIVE
Data sheet Order now

Product details

Number of channels 1 Total supply voltage (+5 V = 5, ±5 V = 10) (min) (V) 2.7 Total supply voltage (+5 V = 5, ±5 V = 10) (max) (V) 5.4 BW at Acl (MHz) 620 Acl, min spec gain (V/V) 1 Slew rate (typ) (V/µs) 1500 Architecture Bipolar, Fully Differential ADC Driver Vn at flatband (typ) (nV√Hz) 2.2 Iq per channel (typ) (mA) 10.1 Rail-to-rail In to V-, Out Vos (offset voltage at 25°C) (max) (mV) 0.45 Operating temperature range (°C) -40 to 125 Iout (typ) (mA) 100 2nd harmonic (dBc) 140 3rd harmonic (dBc) 140 Frequency of harmonic distortion measurement (MHz) 0.1 GBW (typ) (MHz) 850 Input bias current (max) (pA) 13000000 Features Decompensated, Shutdown CMRR (typ) (dB) 100 Rating Catalog
Number of channels 1 Total supply voltage (+5 V = 5, ±5 V = 10) (min) (V) 2.7 Total supply voltage (+5 V = 5, ±5 V = 10) (max) (V) 5.4 BW at Acl (MHz) 620 Acl, min spec gain (V/V) 1 Slew rate (typ) (V/µs) 1500 Architecture Bipolar, Fully Differential ADC Driver Vn at flatband (typ) (nV√Hz) 2.2 Iq per channel (typ) (mA) 10.1 Rail-to-rail In to V-, Out Vos (offset voltage at 25°C) (max) (mV) 0.45 Operating temperature range (°C) -40 to 125 Iout (typ) (mA) 100 2nd harmonic (dBc) 140 3rd harmonic (dBc) 140 Frequency of harmonic distortion measurement (MHz) 0.1 GBW (typ) (MHz) 850 Input bias current (max) (pA) 13000000 Features Decompensated, Shutdown CMRR (typ) (dB) 100 Rating Catalog
VQFN (RGT) 16 9 mm² (3 mm × 3 mm) WQFN (RUN) 10 4 mm² (2 mm × 2 mm)
  • Fully differential amplifier (FDA) architecture
  • Bandwidth: 500MHz (G = 2V/V)
  • Gain bandwidth product: 850MHz
  • Slew rate: 1500V/µs
  • HD2: –95dBc at 10MHz (2VPP, RL = 500Ω)
  • HD3: –90dBc at 10MHz (2VPP, RL = 500Ω)
  • Input voltage noise: 2.2nV/√Hz (f > 100kHz)
  • Low offset drift: ±0.5µV/°C (typical)
  • Negative rail input (NRI)
  • Rail-to-rail output (RRO)
  • Robust operation for Rload ≥ 50Ω
  • Output common-mode control
  • Power supply:
    • Single-supply voltage range: 2.7V to 5.4V
    • Split-supply voltage range: ±1.35V to ±2.7V
    • Quiescent current: 10.1mA (5V supply)
  • Power-down capability: 2µA (typical)
  • Fully differential amplifier (FDA) architecture
  • Bandwidth: 500MHz (G = 2V/V)
  • Gain bandwidth product: 850MHz
  • Slew rate: 1500V/µs
  • HD2: –95dBc at 10MHz (2VPP, RL = 500Ω)
  • HD3: –90dBc at 10MHz (2VPP, RL = 500Ω)
  • Input voltage noise: 2.2nV/√Hz (f > 100kHz)
  • Low offset drift: ±0.5µV/°C (typical)
  • Negative rail input (NRI)
  • Rail-to-rail output (RRO)
  • Robust operation for Rload ≥ 50Ω
  • Output common-mode control
  • Power supply:
    • Single-supply voltage range: 2.7V to 5.4V
    • Split-supply voltage range: ±1.35V to ±2.7V
    • Quiescent current: 10.1mA (5V supply)
  • Power-down capability: 2µA (typical)

The THS4541 is a low-power, voltage-feedback, fully differential amplifier (FDA) with an input common-mode range below the negative rail, and rail-to-rail output. The THS4541 is designed for low-power data acquisition systems where high density is critical in a high-performance analog-to-digital converter (ADC) or digital-to-analog converter (DAC) interface design.

The THS4541 features the negative-rail input required when interfacing a dc-coupled, ground-centered, source signal. This negative-rail input, with rail-to-rail output, allows for easy interface between single-ended, ground-referenced, bipolar signal sources and a wide variety of successive approximation register (SAR), delta-sigma (ΔΣ), or pipeline ADCs using only a single 2.7V to 5.4V power supply.

The THS4541 is characterized for operation over the wide temperature range of –40°C to +125°C and is available in 16-pin VQFN and 10-pin WQFN packages.

The THS4541 is a low-power, voltage-feedback, fully differential amplifier (FDA) with an input common-mode range below the negative rail, and rail-to-rail output. The THS4541 is designed for low-power data acquisition systems where high density is critical in a high-performance analog-to-digital converter (ADC) or digital-to-analog converter (DAC) interface design.

The THS4541 features the negative-rail input required when interfacing a dc-coupled, ground-centered, source signal. This negative-rail input, with rail-to-rail output, allows for easy interface between single-ended, ground-referenced, bipolar signal sources and a wide variety of successive approximation register (SAR), delta-sigma (ΔΣ), or pipeline ADCs using only a single 2.7V to 5.4V power supply.

The THS4541 is characterized for operation over the wide temperature range of –40°C to +125°C and is available in 16-pin VQFN and 10-pin WQFN packages.
filter Find other Fully differential amplifiers
Download View video with transcript Video

Similar products you might be interested in

open-in-new Compare alternates
Similar functionality to the compared device.
THS4541-DIE ACTIVE Bare die 850-MHz precision fully differential amplifier The THS4541-DIE is a bare die version of the device that is designed small systems or for use in multi-chip modules (MCMs).

Technical documentation

No results found. Please clear your search and try again.
View all 14
Top documentation Type Title Format options Date
* Data sheet THS4541 Negative Rail Input, Rail-to-Rail Output, Precision, 850MHz Fully Differential Amplifier datasheet (Rev. B) PDF | HTML Feb 22, 2024
Application note Sampling the DC Bin: Designing DC-Coupled Amplifier Frontends for High-Speed ADCs (Rev. A) PDF | HTML May 4, 2026
Application brief Why Use an FDA to Drive an ADC? PDF | HTML Jan 8, 2026
Application brief Active Filter Design for Differential ADCs (Rev. A) PDF | HTML Oct 8, 2025
Product overview High Speed Amplifiers for In-Vitro Diagnostics (IVD) Analog Front End PDF | HTML Apr 10, 2025
Product overview Pairing ADC Drivers With Fully-Differential Input ADCs for Wide Bandwidth Data Acquisition Apr 1, 2024
Application brief Time of Flight and LIDAR - Optical Front End Design (Rev. A) PDF | HTML Apr 29, 2022
Application note High Speed ADCs and Amplifiers for Flow Cytometry Applications Oct 12, 2020
Application brief Maximizing System Total Harmonic Distortion Using High Speed Amplifiers Jun 20, 2018
E-book The Signal e-book: A compendium of blog posts on op amp design topics PDF | HTML Mar 28, 2017
Application note Design for a Wideband Differential Transimpedance DAC Output (Rev. A) Oct 17, 2016
Design guide Optical Front-End System Design Guide Oct 26, 2015
Analog design Journal Using single-supply fully diff. amps with neg. input voltages to drive ADCs Nov 15, 2010
Analog design Journal Input impedance matching with fully differential amplifiers Oct 22, 2008

Design & development

For additional terms or required resources, click any title below to view the detail page where available.

Evaluation board

ADC3541EVM — ADC3541 evaluation module for single-channel, low-noise, ultra-low-power and low-latency ADC

The ADC3541 evaluation module (EVM) is designed to evaluate the ADC3541 family of high-speed analog-to-digital converters (ADCs). The EVM is populated with the ADC3541, a 14-bit, single-channel 10MSPS ADC with CMOS interface.
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADC3642EVM — ADC3642 evaluation module for dual-channel, 14-bit, 25-MSPS, low-noise, ultra-low-power ADC

The ADC3642 evaluation module (EVM) is designed to evaluate the ADC3642 family of high-speed analog-to-digital converters (ADCs). The EVM is populated with the ADC3642, a 14-bit, dual-channel 25MSPS ADC with serial LVDS interface and allows for evaluation of up to 25MSPS and single or dual channel (...)
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADC3643EVM — ADC3643 evaluation module for dual-channel, 14-bit, 65MSPS, low-noise, ultra-low-power ADC

The ADC3643 evaluation module (EVM) is designed to evaluate the ADC3643 family of high-speed analog-to-digital converters (ADCs). The EVM is populated with the ADC3643, a 14-bit, dual-channel 65MSPS ADC with CMOS interface and allows for evaluation of up to 65MSPS and single or dual channel (...)
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADC3644EVM — ADC3644 evaluation module for dual-channel, 14-bit, 125MSPS, low-noise, ultra-low-power ADC

The ADC3644 evaluation module (EVM) is designed to evaluate the ADC3644 family of high-speed analog-to-digital converters (ADCs). The EVM is populated with the ADC3644, a 14-bit, dual-channel 125MSPS ADC with CMOS interface and allows for evaluation of single or dual channel devices available in (...)
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADC3660EVM — ADC3660 dual, 16-bit, 0.5MSPS to 65MSPS, low-noise, ultra-low-power ADC evaluation module

The ADC3660 evaluation module (EVM) is designed to evaluate the ADC3660 high-speed analog-to-digital converter (ADC). The EVM is populated with the ADC3660, a 16-bit, dual-channel ADC with CMOS interface that can operate up to 65MSPS.
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADC3662EVM — ADC3662 evaluation module for dual-channel, 16-bit, 25-MSPS, low-noise, ultra-low-power ADC

The ADC3662 evaluation module (EVM) is designed to evaluate the ADC3662 family of high-speed analog-to-digital converters (ADCs). The EVM is populated with the ADC3662, a 16-bit, dual-channel 25MSPS ADC with serial LVDS interface and allows for evaluation of up to 25MSPS and single or dual channel (...)
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADC3663EVM — ADC3663 dual-channel, 16-bit, 65MSPS, low-noise, ultra-low-power ADC evaluation module

The ADC3663 evaluation module (EVM) is designed to evaluate the ADC3663 family of high-speed analog-to-digital converters (ADCs). The EVM is populated with the ADC3663, a 16-bit, dual-channel 65MSPS ADC with serial LVDS interface and allows for evaluation of all sample rates and single or dual (...)
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADC3664EVM — ADC3664 dual, 14-bit, 125MSPS, high-SNR, low-power ADC with SLVDS interface evaluation module

The ADC3664 evaluation module (EVM) is designed to evaluate the ADC3664 family of high-speed analog-to-digital converters (ADCs). The EVM is populated with the ADC3664, a 16-bit, dual-channel 125MSPS ADC with serial LVDS interface and allows for evaluation of single or dual channel devices (...)
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADC3683EVM — ADC3683 dual-channel, 18-bit, 65MSPS, low-noise, ultra-low-power ADC evaluation module

The ADC3683 evaluation module (EVM) is designed to evaluate the ADC3683 family of high-speed analog-to-digital converters (ADCs). The EVM is populated with the ADC3683, a 18-bit, dual-channel 65MSPS ADC with serial LVDS interface and allows for evaluation of all sample rates and single or dual (...)
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

ADS9219EVM — ADS9219 evaluation module

The ADS9219 evaluation module (EVM) is a platform for evaluating the performance of the ADS9219, a two-channel, 18-bit, 20MSPS per channel successive approximation register (SAR) analog-to-digital converter (ADC) with integrated ADC driver and voltage reference. The ADS9219EVM includes a discrete (...)
User guide: PDF | HTML
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

THS4541RGTEVM — THS4541 Evaluation Module in RGT Package

The THS4541RGT EVM is an evaluation module for the single THS4541 amplifier in the RGT package. This evaluation module is designed to quickly and easily demonstrate the functionality and versatility of the amplifier. The EVM is ready to connect to power, signal source, and test instruments (...)

User guide: PDF
Supported products & hardware
In stock
Limit:
??asset.out-of-stock-ti_en_US??
Not available
Evaluation board

DEV-ADC34J22 — DEV-ADC34J22 Evaluation Module

The DEV-ADC34J22 is a four-channel, 50MSPS ADC Module designed to integrate with Altera’s HSMC standard. The DEV-ADC34J22 features TI’s new JESD204B compliant ADC34J22 Analog Digital Converter (ADC), with clocking conditioning using TI’s LMK04828 jitter cleaner. It provides (...)

From: Dallas Logic Corporation
Supported products & hardware
Simulation model

OPA858, THS4541 Flow Cytometry Example Front End PSpice Reference Design

SBOMBL1.ZIP (27 KB) - PSpice model
Supported products & hardware
Simulation model

THS4541 PSpice Model (Rev. A)

SBOM932A.ZIP (18 KB) - PSpice model
Supported products & hardware
Simulation model

THS4541 TINA-TI Reference Design (Rev. B)

SBOM907B.TSC (52 KB) - TINA-TI reference design
Supported products & hardware
Simulation model

THS4541 TINA-TI Spice Model (Rev. B)

SBOM906B.ZIP (9 KB) - TINA-TI Spice model
Supported products & hardware
Calculation tool

SBOR022 — TI FDA Calculator

Supported products & hardware
Reference design

TIDA-00294 — Dallas Logic Corp high performance active interface for high-speed ADCs reference design

This reference design, provided by Dallas Logic Corp, uses the ADC34J22 12b 50MSPS JESD204B data converter and the THS4541 fully differential amplifier to show how to design a high-performance active interface for high speed ADCs. This type of circuit can be used in sensor front end, motor control, (...)

Supported products & hardware
Reference design

TIDA-00725 — Wide Bandwidth Optical Front-end Reference Design

This reference design implements and measures a complete 120MHz wide bandwidth optical front end comprising a high speed transimpedance amplifier, fully differential amplifier, and high speed 14-bit 160MSPS ADC with JESD204B interface.  Hardware and software are provided to evaluate the (...)

Supported products & hardware
Reference design

TIDA-00799 — Quad-Channel, 12-Bit, 50-MSPS ADC Reference Design With Low Noise, Low Distortion, DC and AC Inputs

This reference design demonstrates how to implement a single-ended-to-differential input path, which can be AC-coupled or DC-coupled for an ADC3422. It also explains how to design a high-input impedance, DC-coupled input path. The reference design can be used for applications such as low-power (...)
Supported products & hardware
Reference design

TIDA-00942 — 12-bit, 20-MSPS Data Acquisition Reference Design for Digitizer

This reference design enables a cost-effective and low-power data acquisition system that provides an alternative to FPGA-based systems. It features a single-ended, high-impedance input that can be used in a wide number of applications, including portable instrumentation and digitizers.

The (...)

Supported products & hardware
Reference design

TIDA-01187 — LIDAR-Pulsed Time-of-Flight Reference Design Using High-Speed Data Converters

Time-of-flight (ToF) optical methods for measuring distance with high precision are utilized in a variety of applications, such as laser safety scanners, range finders, drones, and guidance systems. This design details the advantages of a high-speed data-converter-based solution, including target (...)
Supported products & hardware
Package Pins CAD symbols, footprints & 3D models
VQFN (RGT) 16 Ultra Librarian
WQFN (RUN) 10 Ultra Librarian
TI's Standard Terms and Conditions for Evaluation Items apply.

Ordering & quality

Support & training

TI E2E™ forums with technical support from TI engineers

View all forum topics

Content is provided "as is" by TI and community contributors and does not constitute TI specifications. See terms of use.

If you have questions about quality, packaging or ordering TI products, see TI support. ​​​​​​​​​​​​​​

Videos